Exposure to mild intermittent hypoxia increases loop gain and the arousal threshold in participants with obstructive sleep apnoea

Author:

Alex Raichel M.12,Panza Gino S.12,Hakim Huzaifa12,Badr M. Safwan123,Edwards Bradley A.45,Sands Scott A.6,Mateika Jason H.123ORCID

Affiliation:

1. John D. Dingell Veterans Affairs Medical Center Detroit MI 48201 USA

2. Department of PhysiologyWayne State University School of Medicine Detroit MI 48201 USA

3. Department of Internal MedicineWayne State University School of Medicine Detroit MI 48201 USA

4. Sleep and Circadian Medicine LaboratoryDepartment of Physiology Monash University Melbourne Australia

5. School of Psychological Sciences and Monash Institute of Cognitive and Clinical NeurosciencesMonash University Melbourne Australia

6. Division of Sleep and Circadian DisordersBrigham and Women's Hospital and Harvard Medical School Boston MA USA

Funder

American Heart Association

National Institutes of Health

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Physiology

Reference55 articles.

1. Long-term facilitation in obstructive sleep apnea patients during NREM sleep

2. Long‐term facilitation of ventilation in humans during NREM sleep;Babcock MA;Sleep,1998

3. Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events

4. Effect of carotid body denervation on arousal response to hypoxia in sleeping dogs

5. Effect of sleep fragmentation on ventilatory and arousal responses of sleeping dogs to respiratory stimuli;Bowes G;Am Rev Respir Dis,1980

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