Rapid desensitization of the rat α7 nAChR is facilitated by the presence of a proline residue in the outer β-sheet

Author:

McCormack Thomas J.,Melis Claudio,Colón José,Gay Elaine A.,Mike Arpad,Karoly Robert,Lamb Patricia W.,Molteni Carla,Yakel Jerrel L.

Publisher

Wiley

Subject

Physiology

Reference47 articles.

1. Non-charged amino acids from three different domains contribute to link agonist binding to channel gating in α7 nicotinic acetylcholine receptors;Aldea;J Neurochem,2007

2. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes;Alkondon;J Pharmacol Exp Ther,1993

3. Allosteric modulation of α7 nicotinic receptors selectively depolarizes hippocampal interneurons, enhancing spontaneous GABAergic transmission;Arnaiz-Cot;Eur J Neurosci,2008

4. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors;Brejc;Nature,2001

5. The Amber biomolecular simulation programs;Case;J Comput Chem,2005

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