Knockdown of mineralocorticoid or angiotensin II type 1 receptor gene expression in the paraventricular nucleus prevents angiotensin II hypertension in rats
Author:
Affiliation:
1. University of Ottawa Heart Institute; Ottawa ON K1Y 4W7 Canada
Funder
Canadian Institutes of Health Research
Publisher
Wiley
Subject
Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1113/jphysiol.2014.275560/fullpdf
Reference46 articles.
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2. Angiotensin II actions in paraventricular nucleus: functional evidence for neurotransmitter role in efferents originating in subfornical organ;Bains;Brain Res,1992
3. Circulating angiotensin II gains access to the hypothalamus and brain stem during hypertension via breakdown of the blood-brain barrier;Biancardi;Hypertension,2014
4. Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signalling in the subfornical organ of the brain;Cao;Hypertension,2012
5. The ligand binding signatures of the rat AT1a, AT1b and the human AT1 receptors are essentially identical;Chiu;Biochem Biophys Res Commun,1993
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