Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403QMYH7mutation-Reference-Cited by-同舟云学术

Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403QMYH7mutation

Published:2014-07-09 Issue:15 Volume:592 Page:3257-3272
ISSN:0022-3751
Container-title:The Journal of Physiology
language:en
Short-container-title:J Physiol

Author:

Witjas-Paalberends E. Rosalie¹,Ferrara Claudia²,Scellini Beatrice²,Piroddi Nicoletta²,Montag Judith³,Tesi Chiara²,Stienen Ger J. M.¹⁴,Michels Michelle⁵,Ho Carolyn Y.⁶,Kraft Theresia³,Poggesi Corrado²,van der Velden Jolanda¹⁷

Affiliation:

1. Department of Physiology; VU University Medical Centre; Amsterdam The Netherlands

2. Department of Experimental and Clinical Medicine; University of Florence; Florence Italy

3. Institute of Molecular and Cell Physiology; Hannover Medical School; Hannover Germany

4. Department of Physics and Astronomy; VU University; Amsterdam The Netherlands

5. Thorax Centre; Cardiology, Erasmus Medical Centre; Rotterdam The Netherlands

6. Brigham and Women's Hospital; Cardiology Boston USA

7. ICIN-Netherlands Heart Institute; Utrecht The Netherlands

Funder

7th Framework Program of the European Union

Netherlands organization for scientific research

Telethon Italy

Deutsche Forschungsgemeinschaft (DFG)

Publisher

Wiley

Subject

Physiology

Reference50 articles.

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3. Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils;Belus;Circ Res,2010

4. The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils;Belus;J Physiol,2008

5. Altered crossbridge kinetics in the MHC403/+ mouse model of familial hypertrophic cardiomyopathy;Blanchard;Circ Res,1999

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