Inhibition of HERG K + Current and Prolongation of the Guinea‐Pig Ventricular Action Potential by 4‐Aminopyridine
Author:
Affiliation:
1. Department of Physiology and Cardiovascular Research Laboratories, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
Publisher
Wiley
Subject
Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.2003.043976
Reference28 articles.
1. Characterization of 4‐aminopyridine block of the transient outward K+ current in adult rat ventricular myocytes;Castle NA;J Pharmacol Exp Ther,1993
2. Transient outward potassium current and repolarization of cardiac cells;Coraboeuf E;Bull Acad Natl Med,1998
3. T wave changes persisting after ventricular pacing in canine heart are altered by 4-aminopyridine but not by lidocaine. Implications with respect to phenomenon of cardiac 'memory'.
4. Frequency-Dependent Effects of 4-Aminopyridine and Almokalant on Action-Potential Duration of Adult and Neonatal Rabbit Ventricular Muscle
5. Characterisation of Kv4.3 in HEK293 cells: comparison with the rat ventricular transient outward potassium current
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