CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect

Author:

Reil Jan‐Christian1ORCID,Reil Gert‐Hinrich2,Kovács Árpád345,Sequeira Vasco6,Waddingham Mark T.7,Lodi Maria345,Herwig Melissa345,Ghaderi Shahrooz3,Kreusser Michael M.8,Papp Zoltán9ORCID,Voigt Niels101112ORCID,Dobrev Dobromir10,Meyhöfer Svenja13ORCID,Langer Harald F.1,Maier Lars S.14,Linz Dominik15,Mügge Andreas45,Hohl Mathias15,Steendijk Paul16,Hamdani Nazha34517

Affiliation:

1. Klinik für Innere Medizin II Kardiologie Angiologie und Internistische Intensivmedizin Universitäres Herzzentrum Lübeck, Universitätsklinikum Schleswig‐Holstein Campus Lübeck Lübeck Germany

2. Klinik für Kardiologie Klinikum Oldenburg Innere Medizin I Oldenburg Germany

3. Institute of Physiology Ruhr University Bochum Bochum Germany

4. Department of Cardiology St. Josef‐Hospital Ruhr University of Bochum Bochum Germany

5. Molecular and Experimental Cardiology Ruhr Universität Bochum Bochum Germany

6. Comprehensive Heart Failure Center (CHFC) University Clinic Würzburg Germany

7. Department of Physiology Amsterdam UMC Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences Amsterdam The Netherlands

8. Departments of Cardiology University of Heidelberg Heidelberg Germany

9. Division of Clinical Physiology Department of Cardiology Faculty of Medicine University of Debrecen Debrecen Hungary

10. Institute of Pharmacology West German Heart and Vascular Center Faculty of Medicine University Duisburg‐Essen Essen Germany

11. Institute of Pharmacology and Toxicology University Medical Center Göttingen Georg‐August University Göttingen Göttingen Germany

12. DZHK (German Center for Cardiovascular Research), partner site Göttingen Göttingen Germany

13. Institute for Endocrinology & Diabetes University of Lübeck Lübeck, Germany and German Center for Diabetes Research Neuherberg Germany

14. Klinik und Poliklinik für innere Medizin II Universitätsklinikum Regensburg Regensburg Germany

15. Klinik für Innere Medizin III (Kardiologie Angiologie Internistische Intensivmedizin) Universitätsklinikum des Saarlandes Homburg/Saar Germany

16. Departments of Cardiology Leiden University Medical Center Leiden The Netherlands

17. Department Clinical Pharmacology Ruhr University of Bochum Bochum Germany

Funder

National Institutes of Health

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Physiology

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