High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts

Author:

Fu Qin12ORCID,Hu Yuting12,Wang Qingtong34,Liu Yongming35,Li Ning6,Xu Bing3,Kim Sungjin3ORCID,Chiamvimonvat Nipavan67ORCID,Xiang Yang K.357

Affiliation:

1. Department of Pharmacology, School of Basic Medicine, Tongji Medical College; Huazhong University of Science and Technology; Wuhan China

2. The Key Laboratory for Drug Target Research and Pharmacodynamic Evaluation of Hubei Province; Wuhan China

3. Department of Pharmacology; University of California; Davis CA USA

4. Institute of Clinical Pharmacology, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Collaborative Innovation Centre of Anti-inflammatory and Immune Medicine; Anhui Medical University; Hefei China

5. Shuguang Hospital; Shanghai University of Traditional Chinese Medicine; Shanghai China

6. Division of Cardiovascular Medicine, Department of Medicine; University of California; Davis CA USA

7. VA Northern California Healthcare System; Mather CA USA

Funder

National Natural Science Foundation of China

National Institutes of Health

American Heart Association

Shanghai Eastern Scholar

Publisher

Wiley

Subject

Physiology

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