Hyperandrogenism and insulin resistance‐induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome-Reference-Cited by-同舟云学术

Hyperandrogenism and insulin resistance‐induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome

Published:2019-07-03 Issue:15 Volume:597 Page:3927-3950
ISSN:0022-3751
Container-title:The Journal of Physiology
language:en
Short-container-title:J Physiol

Author:

Zhang Yuehui¹²,Zhao Wei¹,Xu Hongfei¹,Hu Min²³⁴,Guo Xiaozhu¹,Jia Wenyan¹,Liu Guoqi¹,Li Juan²³,Cui Peng²,Lager Susanne⁵,Sferruzzi‐Perri Amanda Nancy⁶^ORCID,Li Wei¹,Wu Xiao‐ke¹,Han Yanhua¹,Brännström Mats⁷,Shao Linus R²^ORCID,Billig Håkan²

Affiliation:

1. Department of Obstetrics and GynecologyKey Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine 150040 Harbin China

2. Department of Physiology/EndocrinologyInstitute of Neuroscience and PhysiologyThe Sahlgrenska AcademyUniversity of Gothenburg 40530 Gothenburg Sweden

3. Department of Traditional Chinese MedicineThe First Affiliated Hospital of Guangzhou Medical University 510120 Guangzhou China

4. Institute of Integrated Traditional Chinese Medicine and Western MedicineGuangzhou Medical University 510120 Guangzhou China

5. Department of Women's and Children's HealthUppsala University 75185 Uppsala Sweden

6. Centre for Trophoblast ResearchDepartment of PhysiologyDevelopment and NeuroscienceUniversity of Cambridge Cambridge CB2 3EG UK

7. Department of Obstetrics and GynecologySahlgrenska University HospitalSahlgrenska AcademyUniversity of Gothenburg 41345 Gothenburg Sweden

Funder

Medicinska Forskningsrådet

Knut och Alice Wallenbergs Stiftelse

Adlerbertska Stiftelserna

Publisher

Wiley

Subject

Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1113/JP277879

Reference84 articles.

1. The effects of oxidative stress on female reproduction: a review

2. Review: Alterations in placental glycogen deposition in complicated pregnancies: Current preclinical and clinical evidence

3. N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why

4. Polycystic ovary syndrome

5. Transcriptome Analysis of the Dihydrotestosterone-Exposed Fetal Rat Gubernaculum Identifies Common Androgen and Insulin-Like 3 Targets1

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