Author:
Yoon Young Chae,Cho Soo Yeon,Park Sun Kyoung,Yoo Young Sik,Whang Woong Joo,Na Kyung Sun,Kim Eun Chul,Kim Hyun Seung,Hwang Ho Sik
Abstract
Purpose: To compare the degree of meibomian gland drop-out associated with Demodex infestation using non-contact meibography.Methods: We performed noncontact meibography using an infrared digital camera on 24 adult subjects infested by Demodex and 40 without infestation. The right upper and lower lids were scored based on the loss of meibomian glands, and the scores of the upper and lower eyelids were summed to obtain the total meiboscore for each subject. Meiboscores were evaluated according to Demodex infestation and gender in each group.Results: Sixty-four eyes of 64 people were enrolled in this study. The study subjects had an average age of 67.9 years (range, 40-79 years; men, 65.2 years; women, 69.1 years). There was a significant association between Demodex infestation and total meiboscore and upper and lower eyelid meiboscores (p = 0.000, p = 0.002, p = 0.004, respectively). There was no significant difference in the meiboscores between men and women. Age and meiboscore suggested a weak positive correlation; however, the R2 value was low, due to the concentrated age distribution of the study population.Conclusions: Based on noncontact meibography, the authors concluded that the prevalence of changes in the meibomian glands was significantly related to Demodex infestation; however, there was no significant difference between men and women.
Funder
Korea Health Industry Development Institute
Ministry of Health & Welfare, Republic of Korea
National Research Foundation of Korea
Ministry of Education, Republic of Korea
Sodam Scholarship Foundation of Busan Sungmo Eye Hospital
Publisher
Korean Ophthalmological Society