Comparison of Ocular Biometric Measurements Using New Swept-source Optical-coherence Tomography, Low-coherence Reflectometry, A-Scan Biometry, and Autokeratometry

Abstract

Purpose: We compared optical biometric measurements made using new swept-source optical-coherence tomography, low-coherence reflectometry, autokeratometry, and A-scan biometry.Methods: In total, 86 eyes of 47 patients were included. Axial length, lens thickness, central corneal thickness, anterior chamber depth, and corneal curvature were measured using the Anterion^® (Heidelberg Engineering, inc., Heidelberg, Germany) and Lenstar LS 900^® (Haag-Streit AG, Koeniz, Switzerland) platforms. Corneal curvature and axial length were measured using the Essilor AKR 750^® (Essilor instruments, France, Charenton-le-Pont) and PacScan 300A^® (Sonomed Inc., Chicago, IL, USA) platforms, respectively. The evaluated biometric parameters were compared and verified; intraclass correlation coefficients and Bland-Altman plots were used to analyze statistical agreement.Results: The differences between the Anterion^® and Lenstar LS 900^® platforms in terms of axial length, lens thickness, central corneal thickness, anterior chamber depth, and white-to-white diameter were -0.02 ± 0.08, 0.08 ± 0.13, -2.66 ± 11.12, 0.05 ± 0.12, and 0.08 ± 0.26, respectively. All values were statistically significant. The mean corneal curvature between Anterion^® and Lenstar LS 900^® had a statistically significant difference of -0.08 ± 0.47, while the difference between the Anterion^® and AKR 750^® platforms was not significant. Biometric parameters measured using an Anterion^® and other devices showed a strong positive correlation when assessed using Pearson’s correlation analysis; there was good agreement between the results when analyzed using intraclass correlation coefficients and Bland-Altman plots.Conclusions: Optical biometric measurements made using the Anterion^® platform were not significantly different from those obtained using other devices, but there were significant differences compared to the Lenstar LS 900^® platform. Since these significant differences could influence decision making during intraocular lens selection for cataract surgery, the values are clinically useful for reference.