COVID-19’da Hemoglobin, Ortalama Trombosit Hacimleri ve Nötrofil Lenfosit Oranındaki Değişiklikler

Abstract

Objective: It is aimed to evaluate the changes in blood and inflammatory markers (Mean Platelet Volume and Neutrophil Lymphocyte Ratio) in COVID-19. Method: We studied a total of 213 patients. 142 of them consist of patients who have undergone PCR test due to COVID-19 complaints and have a definite diagnosis. The blood values of 71 healthy people of similar age and characteristics without any complaints or symptoms were retrospectively compared. Results: The mean age of the COVID-19(+) group was 54.62±17.71 years, while the COVID-19(-) group was 50.54±15.74 years. 52.8% (n:75) of the patient group and 54.9% (n:39) of the COVID-19(-) group were women. There was a decrease in the number of platelets especially in the PCR(+) group, but statistically no significant difference was observed between the PCR(+) group and the COVID-19(-) group for hemoglobin and platelet values (p>0.05). However, a significant difference (p <0.01) was found in Mean Platelet Volume, neutrophil, lymphocyte and Neutrophil Lymphocyte Ratio. Conclusion: Due to the cytokine storm that develops in COVID-19 infection, a number of changes occur in the blood, especially a decrease in thrombocyte counts. We think that especially the changes in Mean Platelet Volume and Neutrophil Lymphocyte Ratio, which are new inflammatory markers, can be used in the follow-up of this disease and its prognosis.