Green Biosynthesis of Nanoparticles for Targeted Drug Delivery

Abstract

The matter at its molecular or atomic level is engineered and manufactured through a technique called Nanotechnology. It has contributed in various fields of science, including material science, biology, chemistry, and engineering. Various research studies have suggested that crude extract of plant can enhance the activity of green synthesized nanoparticles (NPs), like gold (Au) and silver (Ag). However, one drawback of NPs is its toxicity. The altered size, shape or surface chemistry of NPs help in passive or active drug targeting. If the size, shape or surface chemistry of NPs is altered, drug targeting can be helped passively or actively. Changing the size, shape or surface chemistry of NPs can help drug targeting actively or passively. On the other hand, green synthesis is said to be environment friendly in which extract of plant is used as capping as well as a reducing agent. So, green synthesis of NPs is important when studying different pathogens. In recent years, nanotechnology has been applied in treating health-related problems, which showed promising results, mainly in the treatment of cancer. The present review discusses the historical and the latest development, drawbacks, , and the challenges faced in the field of green biosynthesis of NPs, along with its wide application.