Cytochrome P450 enzymes: Novel options for cancer therapeutics
Author:
Affiliation:
1. 1Pathology and Departments of
2. 2Molecular and Cell Biology, University of Aberdeen, Aberdeen, United Kingdom
Abstract
Publisher
American Association for Cancer Research (AACR)
Subject
Cancer Research,Oncology
Link
https://aacrjournals.org/mct/article-pdf/3/3/363/1867732/363-371.pdf
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4. Gut I, Danielova V, Holubova J, Soucek P, Kluckova H. Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: effects of concentration, time and cytochrome P450-catalyzed metabolism. Arch Toxicol 2000;74:437–46.
5. Huang Z, Roy P, Waxman DJ. Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide. Biochem Pharmacol 2000;59:61–72.
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