Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS

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Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS–ERK Signaling

Published:2014-01-16 Issue:3 Volume:4 Page:334-347
ISSN:2159-8274
Container-title:Cancer Discovery
language:en
Short-container-title:Cancer Discovery

Author:

Will Marie,Qin Alice Can Ran,Toy Weiyi,Yao Zhan,Rodrik-Outmezguine Vanessa,Schneider Claudia,Huang Xiaodong,Monian Prashant,Jiang Xuejun,de Stanchina Elisa,Baselga José,Liu Ningshu,Chandarlapaty Sarat,Rosen Neal

Publisher

American Association for Cancer Research (AACR)

Subject

Oncology

Cited by 169 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Assessments of prostate cancer cell functions highlight differences between a pan‐PI3K/mTOR inhibitor, gedatolisib, and single‐node inhibitors of the PI3K/AKT/mTOR pathway;Molecular Oncology;2024-08-02

2. A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance;Nature Cancer;2024-07-11

3. eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer;2024-05-11

4. Chondroprotective effects of Apolipoprotein D in knee osteoarthritis mice through the PI3K/AKT/mTOR signaling pathway;International Immunopharmacology;2024-05

5. Simultaneous inhibition of PI3K and PAK in preclinical models of neurofibromatosis type 2-related schwannomatosis;Oncogene;2024-02-09

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