Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia

Author:

McMahon Christine M.,Ferng Timothy,Canaani Jonathan,Wang Eunice S.,Morrissette Jennifer J.D.ORCID,Eastburn Dennis J.,Pellegrino MaurizioORCID,Durruthy-Durruthy Robert,Watt Christopher D.,Asthana Saurabh,Lasater Elisabeth A.,DeFilippis RosaAnna,Peretz Cheryl A.C.,McGary Lisa H.F.,Deihimi Safoora,Logan Aaron C.,Luger Selina M.,Shah Neil P.,Carroll Martin,Smith Catherine C.,Perl Alexander E.ORCID

Funder

HHS | NIH | National Center for Advancing Translational SciencesHHS | NIH | National Center for Advancing Translational Sciences (NCATS)

American Society of Clinical OncologyAmerican Society of Clinical Oncology (ASCO)

HHS | NIH | National Cancer InstituteHHS | NIH | National Cancer Institute (NCI)

Damon Runyon Cancer Research FoundationDamon Runyon Cancer Research Foundation (Damon Runyon)

Biff Ruttenberg Foundation

Publisher

American Association for Cancer Research (AACR)

Subject

Oncology

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