Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation

Author:

Kamata-Sakurai MikaORCID,Narita Yoshinori,Hori Yuji,Nemoto Takayuki,Uchikawa Ryo,Honda Masaki,Hironiwa Naoka,Taniguchi Kenji,Shida-Kawazoe Meiri,Metsugi Shoichi,Miyazaki Taro,Wada Naoko A.,Ohte Yuki,Shimizu Shun,Mikami Hirofumi,Tachibana Tatsuhiko,Ono Natsuki,Adachi Kenji,Sakiyama Tetsushi,Matsushita Tomochika,Kadono Shojiro,Komatsu Shun-ichiro,Sakamoto Akihisa,Horikawa Sayuri,Hirako Ayano,Hamada Koki,Naoi Sotaro,Savory NasaORCID,Satoh Yasuko,Sato Motohiko,Noguchi Yuki,Shinozuka Junko,Kuroi Haruka,Ito Ami,Wakabayashi TetsuyaORCID,Kamimura Masaki,Isomura Fumihisa,Tomii Yasushi,Sawada Noriaki,Kato Atsuhiko,Ueda Otoya,Nakanishi Yoshito,Endo Mika,Jishage Kou-ichi,Kawabe YoshikiORCID,Kitazawa Takehisa,Igawa Tomoyuki

Funder

F. Hoffmann-La Roche AG | Chugai Pharmaceutical

Publisher

American Association for Cancer Research (AACR)

Subject

Oncology

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