Affiliation:
1. Department of Molecular Genetics, Albet Einstein College of Medicine, Bronx, New York
Abstract
Abstract
Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer. [Cancer Res 2008;68(14):5505–7]
Publisher
American Association for Cancer Research (AACR)
Cited by
80 articles.
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