Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4

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Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4–LEF1 Binding

Published:2021-02-19 Issue:5 Volume:19 Page:823-833
ISSN:1541-7786
Container-title:Molecular Cancer Research
language:en
Short-container-title:Mol Cancer Res

Author:

Lanauze Claudia B.,Sehgal Priyanka^ORCID,Hayer Katharina^ORCID,Torres-Diz Manuel^ORCID,Pippin James A.^ORCID,Grant Struan F.A.^ORCID,Thomas-Tikhonenko Andrei^ORCID

Funder

NIH

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology,Molecular Biology

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies;International Journal of Molecular Sciences;2024-08-30

2. Exploring the molecular mechanisms and therapeutic potential of SMAD4 in colorectal cancer;Cancer Biology & Therapy;2024-08-20

3. Loss of functionSMAD4nonstop mutations in human cancer;Histopathology;2023-03-14

4. Efficient Bioinspired Feature Selection and Machine Learning Based Framework Using Omics Data and Biological Knowledge Data Bases in Cancer Clinical Endpoint Prediction;IEEE Access;2023

5. MYC Hyperactivates Wnt Signaling in APC/CTNNB1-Mutated Colorectal Cancer Cells through miR-92a–Dependent Repression of DKK3;Molecular Cancer Research;2021-09-30

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