Affiliation:
1. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
Abstract
Summary:
In this issue of Blood Cancer Discovery, Umeda and colleagues identify and comprehensively analyze a novel recurrent UBTF mutation (tandem duplications) in pediatric acute myeloid leukemia. Acute myeloid leukemia cases with UBTF tandem duplications display distinctive biologic features, including association with FLT3-ITD and WT1 mutations and high-risk disease, and appear to represent a new genetic subtype of acute myeloid leukemia.
See related article by Umeda et al., p. 194 (7).
Publisher
American Association for Cancer Research (AACR)
Cited by
1 articles.
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