Double-Stranded RNA to Mimic Viral Infection for Cancer Immunotherapy-Reference-Cited by-同舟云学术

Double-Stranded RNA to Mimic Viral Infection for Cancer Immunotherapy

Published:2024-06-13 Issue:16 Volume:30 Page:3355-3357
ISSN:1078-0432
Container-title:Clinical Cancer Research
language:en
Short-container-title:

Author:

Martínez-Riaño Ana¹^ORCID,Mosteo Laura¹²^ORCID,Molero-Glez Paula¹^ORCID,Márquez-Rodas Iván³^ORCID,Melero Ignacio¹²⁴⁵⁶^ORCID

Affiliation:

1. Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain. 1

2. Cancer Center Clínica Universidad de Navarra (CCUN), Pamplona, Spain. 2

3. Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid, Spain. 3

4. Navarra Institute for Health Research (IDISNA), Pamplona, Spain. 4

5. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. 5

6. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. 6

Abstract

Summary The presence of moieties denoting viral infection is crucial to mount powerful cytotoxic T-cell immune responses acting through innate receptors such as Toll-like receptor 3. For cancer immunotherapy, several safe analogues of viral double-stranded RNA are under clinical development following compelling evidence for efficacy in mouse models. See related article by van Eijck et al., p. 3447

Funder

European funds for regional development

European Union MSCA-2023-PF

Instituto de Salud Carlos III

Ministerio de Ciencia e Innovación

Publisher

American Association for Cancer Research (AACR)

Link

https://aacrjournals.org/clincancerres/article-pdf/doi/10.1158/1078-0432.CCR-24-0938/3462182/ccr-24-0938.pdf

Reference21 articles.

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5. Expansion and activation of CD103(+) dendritic cell Progenitors at the tumor site enhances tumor responses to therapeutic PD-L1 and BRAF inhibition;Salmon;Immunity,2016