HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma-Reference-Cited by-同舟云学术

HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma

Published:2019-11-14 Issue:4 Volume:26 Page:793-803
ISSN:1078-0432
Container-title:Clinical Cancer Research
language:en
Short-container-title:Clin Cancer Res

Author:

Courtney Kevin D.^ORCID,Ma Yuanqing,Diaz de Leon Alberto,Christie Alana,Xie Zhiqun^ORCID,Woolford Layton,Singla Nirmish,Joyce Allison,Hill Haley,Madhuranthakam Ananth J.,Yuan Qing,Xi Yin^ORCID,Zhang Yue,Chang Jenny,Fatunde Oluwatomilade,Arriaga Yull,Frankel Arthur E.,Kalva Sanjeeva,Zhang Song,McKenzie Tiffani,Reig Torras Oscar,Figlin Robert A.,Rini Brian I.,McKay Renée M.,Kapur Payal,Wang Tao,Pedrosa Ivan,Brugarolas James

Funder

Cancer Prevention and Research Institute of Texas

NIH

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology

Cited by 113 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel small molecule inhibitors targeting renal cell carcinoma: Status, challenges, future directions;European Journal of Medicinal Chemistry;2024-03

2. Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity;BMJ Oncology;2024-02

3. Novel Approaches with HIF-2α Targeted Therapies in Metastatic Renal Cell Carcinoma;Cancers;2024-01-31

4. Metabolic alterations in hereditary and sporadic renal cell carcinoma;Nature Reviews Nephrology;2024-01-22

5. FKBP10 promotes clear cell renal cell carcinoma progression and regulates sensitivity to the HIF2α blockade by facilitating LDHA phosphorylation;Cell Death & Disease;2024-01-17