Ion channel mRNA distribution and expression in the sinoatrial node and right atrium of dogs and monkeys
Author:
Affiliation:
1. Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
https://www.jstage.jst.go.jp/article/tox/34/3/34_2020-0089/_pdf
Reference9 articles.
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2. 2. Huang H, Pugsley MK, Fermini B, Curtis MJ, Koerner J, Accardi M, and Authier S. Cardiac voltage-gated ion channels in safety pharmacology: Review of the landscape leading to the CiPA initiative. J Pharmacol Toxicol Methods. 87: 11–23. 2017.
3. 3. Aziz Q, Li Y, and Tinker A. Potassium channels in the sinoatrial node and their role in heart rate control. Channels (Austin). 12: 356–366. 2018.
4. 4. Wang F, Flanagan J, Su N, Wang LC, Bui S, Nielson A, Wu X, Vo HT, Ma XJ, and Luo Y. RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. J Mol Diagn. 14: 22–29. 2012.
5. 5. Zicha S, Fernández-Velasco M, Lonardo G, L’Heureux N, and Nattel S. Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model. Cardiovasc Res. 66: 472–481. 2005.
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