Pulmonary Edema Due to Oral Gavage in a Toxicological Study Related to Aquaporin-1, -4 and -5 Expression

Author:

SINGHA Ornuma1,KENGKOOM Kanchana2,CHAIMONGKOLNUKUL Khuanjit2,CHERDYU Sompong2,PONGPONRATN Emsri3,KETJAREON Taweesak1,PANAVECHKIJKUL Yaowaluk1,AMPAWONG Sumate13

Affiliation:

1. Veterinary Medical Care Office, National Laboratory Animal Center, Mahidol University, 999 Salaya, Puttamonthon, Nakhon Pathom 73170, Thailand

2. Academic Services Office, National Laboratory Animal Center, Mahidol University, 999 Salaya, Puttamonthon, Nakhon Pathom 73170, Thailand

3. Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Reference45 articles.

1. 1. OECD Test Guideline 408. Subchronic oral toxicity ––Rodent: 90-day. In: OECD Guideline for the Testing of Chemicals. Organization for Economic Cooperation & Development, Paris. 1998.

2. 2. OECD Test Guideline 420. Acute oral toxicity ––Fixed dose procedure. In: OECD Guideline for the Testing of Chemicals. Organization for Economic Cooperation & Development, Paris. 2001.

3. 3. OECD Test Guideline 452. Chronic toxicity studies. In: OECD Guideline for the Testing of Chemicals. Organization for Economic Cooperation & Development, Paris. 2008.

4. 4. Damsch S, Eichenbaum G, Tonelli A, Lammens L, Van den Bulck K, Feyen B, Vandenberghe J, Megens A, Knight E, and Kelley M. Gavage-related reflux in rats: identification, pathogenesis, and toxicological implications (review). Toxicol Pathol. 39: 348–360. 2011.

5. 5. Conybeare G, and Leslie GB. Improved oral dosing technique for rats. J Pharmacol Methods. 19: 109–116. 1988.

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