Heterogeneous Liver Lobe Responses of Carbon Tetrachloride-Induced Hepatotoxicity in Male Rats Pretreated with Hepatic Enzyme-Inducing Agents
Author:
Affiliation:
1. Developmental Research Laboratories, Shionogi & Co., Ltd.
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
https://www.jstage.jst.go.jp/article/tox/17/4/17_4_223/_pdf
Reference27 articles.
1. 1. Brattin WJ, Glende EA Jr, and Recknagel RO. Pathological mechanisms in carbon tetrachloride hepatotoxicity. J Free Radic Biol Med 1985; 1: 27-38.
2. 2. Slater TF. Necrogenic action of carbon tetrachloride in the rat: a speculative mechanism based on activation. Nature (London) 1966; 209: 113-123.
3. 3. McCay PB, Lai EK, Poyer JL, DuBose CM, and Janzen EG. Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro. J Biol Chem 1984; 259: 2135-2143.
4. 4. Lindros KO, Cai YA, and Penttila KE. Role of ethanol-inducible cytochrome P-450 IIE1 in carbon tetrachloride-induced damage to centrilobular hepatocytes from ethanol-treated rats. Hepatology 1990; 12: 1092-1097.
5. 5. Raucy JL, Kraner JC, and Lasker JM. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. Crit Rev Toxicol 1993; 23: 1-20.
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