A Case of Spontaneous Malignant Hibernoma in a Crl:CD(SD)IGS Rat
Author:
Affiliation:
1. Drug Safety Research Laboratories, Astellas Pharma Inc.
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
http://www.jstage.jst.go.jp/article/tox/22/3/22_3_205/_pdf
Reference12 articles.
1. 1. Poulet FM, Berardi MR, Halliwell W, Hartman B, Auletta C, and Bolte H. Development of hibernomas in rats dosed with phentolamine mesylate during the 24-month carcinogenicity study. Toxicol Pathol. 32: 558-566. 2004.
2. 2. Chandra S, Dochterman W, Ploch S, Torrey C, Cummings CA, Peterson R, et al. A carcinogenicity study with unusually high incidence of spontaneous hibernomas in Wistar-Han rats. Society of Toxicologic Pathology, annual meeting, San Francisco, CA. Poster No.14. 2008.
3. 3. Coleman GL. Four intrathoracic hibernomas in rats. Vet Pathol. 17: 634-637. 1980.
4. 4. Stefanski SA, Elwell MR, and Yoshitomi K. Malignant hibernoma in a Fischer 344 rat. Lab Anim Sci. 37: 347-350. 1987.
5. 5. Al Zubaidy AJ and Finn JP. Brown fat tumours (hibernomas) in rats: histopathological and ultrastructural study. Lab Anim. 17: 13-17. 1983.
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