Establishment of an Invasive Prostate Cancer Model in Transgenic Rats by Intermittent Testosterone Administration

Author:

Sato Shinya1,Suzuki Shugo1,Naiki-Ito Aya1,Komiya Masami1,Ne Long1,Kato Hiroyuki1,Sagawa Hiroyuki1,Yamashita Yoriko1,Shirai Tomoyuki1,Takahashi Satoru1

Affiliation:

1. Department of Experimental Pathology and Tumor Biology

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Reference25 articles.

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3. 3. Zhang J, Dhakal IB, Zhao Z, and Li L. Trends in mortality from cancers of the breast, colon, prostate, esophagus, and stomach in East Asia: role of nutrition transition. Eur J Cancer Prev. 21: 480–489. 2012.

4. 4. Shirai T, Fukushima S, Ikawa E, Tagawa Y, and Ito N. Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2’-dimethyl-4-aminobiphenyl and ethinyl estradiol. Cancer Res. 46: 6423–6426. 1986.

5. 5. Shirai T, Tamano S, Kato T, Iwasaki S, Takahashi S, and Ito N. Induction of invasive carcinomas in the accessory sex organs other than the ventral prostate of rats given 3,2’-dimethyl-4-aminobiphenyl and testosterone propionate. Cancer Res. 51: 1264–1269. 1991.

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