Pathology and Neurotoxicity in Dogs after Repeat Dose Exposure to a Serotonin 5-HT<sub>1B</sub> Inhibitor-Reference-Cited by-同舟云学术

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Pathology and Neurotoxicity in Dogs after Repeat Dose Exposure to a Serotonin 5-HT_1B Inhibitor

Published:2014 Issue:1 Volume:27 Page:31-42
ISSN:0914-9198
Container-title:Journal of Toxicologic Pathology
language:en
Short-container-title:J Toxicol Pathol

Author:

Chang Jane C.F.¹,Ciaccio Paul¹²,Schroeder Patricia¹³,Wright Lindsay¹,Westwood Russell¹,Berg Anna-Lena¹⁴

Affiliation:

1. AstraZeneca R&D

2. Cubist Pharmaceuticals

3. EMD Serono

4. MPA, Läkemedelsverket

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Link

https://www.jstage.jst.go.jp/article/tox/27/1/27_2013-0033/_pdf

Reference36 articles.

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2. 2. Fink KB, and Göthert M. 5-HT receptor regulation of neurotransmitter release. Pharmacol Rev. 59: 360–417. 2007.

3. 3. Moret C, and Briley M. The possible role of 5-HT_1B/1D receptors in psychiatric disorders and their potential as a target for therapy. Eur J Pharmacol. 404: 1–12. 2000.

4. 4. Slassi A. Recent advances in 5-HT_1B/1D receptor antagonists and agonists and their potential therapeutic applications. Curr Top Med Chem. 2: 559–574. 2002.

5. 5. Varnäs K, Nybert S, Karlsson P, Pierson ME, Kågedal M, Cselényi Z, McCarthy D, Xiao A, Zhang M, Halldin C, and Farde L. Dose-dependent binding of AZD3783 to brain 5- HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369. Psychopharmacology. 213: 533–545. 2011.

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