Tissue-specific effects of an anti-desmoglein-3 ADCC antibody due to expression of the target antigen and physiological characteristics of the mouse vagina
Author:
Affiliation:
1. Forerunner Pharma Research Co., Ltd., Komaba Open Laboratory, The University of Tokyo, 6-1 Komaba 4, Meguro, Tokyo 153-8904, Japan
2. Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
https://www.jstage.jst.go.jp/article/tox/33/2/33_2019-0040/_pdf
Reference28 articles.
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2. 2. Leach MW, Halpern WG, Johnson CW, Rojko JL, MacLachlan TK, Chan CM, Galbreath EJ, Ndifor AM, Blanset DL, Polack E, and Cavagnaro JA. Use of tissue cross-reactivity studies in the development of antibody-based biopharmaceuticals: history, experience, methodology, and future directions. Toxicol Pathol. 38: 1138–1166. 2010.
3. 3. Fukuoka J, Dracheva T, Shih JH, Hewitt SM, Fujii T, Kishor A, Mann F, Shilo K, Franks TJ, Travis WD, and Jen J. Desmoglein 3 as a prognostic factor in lung cancer. Hum Pathol. 38: 276–283. 2007.
4. 4. Chen YJ, Chang JT, Lee L, Wang HM, Liao CT, Chiu CC, Chen PJ, and Cheng AJ. DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. Acta Histochem. 116: 803–809. 2014.
5. 5. Fang WK, Chen B, Xu XE, Liao LD, Wu ZY, Wu JY, Shen J, Xu LY, and Li EM. Altered expression and localization of desmoglein 3 in esophageal squamous cell carcinoma. Acta Histochem. 116: 803–809. 2014.
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