Immunohistochemical characterization of oxidative stress in the lungs of rats exposed to the humidifier disinfectant polyhexamethylene guanidine hydrochloride
Author:
Affiliation:
1. Pathology Department, Inhalation Toxicity Research Center, Chemicals Research Bureau, Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, 339-30 Expo-ro, Yuseong-gu, Daejeon 34122, Republic of Korea
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
https://www.jstage.jst.go.jp/article/tox/32/4/32_2019-0049/_pdf
Reference21 articles.
1. 1. Asiedu-Gyekye IJ, Mahmood SA, Awortwe C, and Nyarko AK. A preliminary safety evaluation of polyhexamethylene guanidine hydrochloride. Int J Toxicol. 33: 523–531. 2014.
2. 2. Song JA, Park HJ, Yang MJ, Jung KJ, Yang HS, Song CW, and Lee K. Polyhexamethyleneguanidine phosphate induces severe lung inflammation, fibrosis, and thymic atrophy. Food Chem Toxicol. 69: 267–275. 2014.
3. 3. Park DU, Ryu SH, Lim HK, Kim SK, Choi YY, Ahn JJ, Lee E, Hong SB, Do KH, Cho JL, Bae MJ, Shin DC, Paek DM, and Hong SJ. Types of household humidifier disinfectant and associated risk of lung injury (HDLI) in South Korea. Sci Total Environ. 596-597: 53–60. 2017.
4. 4. Committee on the Investigation of Lung Damage. Korea Centers for Disease Control and Prevention, Ministry of Health and Welfare, White book on health damage outbreak by humidifier disinfectants. Hanrimwon, Seoul, 2014. (In Korean).
5. 5. Lee JH, Kim YH, and Kwon JH. Fatal misuse of humidifier disinfectants in Korea: importance of screening risk assessment and implications for management of chemicals in consumer products. Environ Sci Technol. 46: 2498–2500. 2012.
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