Histopathological evaluation of crypt fission during intestinal development in neonatal mice

Author:

Yamazaki Masaki1,Fujii Etsuko12,Watanabe Takeshi3,Kato Atsuhiko1,Suzuki Masami12

Affiliation:

1. Research Division, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan

2. Forerunner Pharma Research Co., Ltd., Komaba Open Laboratory, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan

3. Chugai Research Institute for Medical Science, Inc, 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Reference21 articles.

1. 1. Remick AK, Catlin NR, Quist EM, Steinbach TJ, and Dixon D. Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists. Toxicol Pathol. 43: 1166–1171. 2015.

2. 2. Dauça M, Bouziges F, Colin S, Kedinger M, Keller MK, Schilt J, Simon-Assmann P, and Haffen K. Development of the vertebrate small intestine and mechanisms of cell differentiation. Int J Dev Biol. 34: 205–218. 1990.

3. 3. Walthall K, Cappon GD, Hurtt ME, and Zoetis T. Postnatal development of the gastrointestinal system: a species comparison. Birth Defects Res B Dev Reprod Toxicol. 74: 132–156. 2005.

4. 4. Cummins AG, Catto-Smith AG, Cameron DJ, Couper RT, Davidson GP, Day AS, Hammond PD, Moore DJ, and Thompson FM. Crypt fission peaks early during infancy and crypt hyperplasia broadly peaks during infancy and childhood in the small intestine of humans. J Pediatr Gastroenterol Nutr. 47: 153–157. 2008.

5. 5. Park HS, Goodlad RA, Ahnen DJ, Winnett A, Sasieni P, Lee CY, and Wright NA. Effects of epidermal growth factor and dimethylhydrazine on crypt size, cell proliferation, and crypt fission in the rat colon. Cell proliferation and crypt fission are controlled independently. Am J Pathol. 151: 843–852. 1997.

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