1. Toxicology Research Department, Pharmaceutical Development Research Laboratories, Teijin Pharma Limited, 4-3-2 Asahigaoka, Hino-shi, Tokyo 191-8512, Japan
2. Safety Research Laboratory, Shin Nippon Biomedical Laboratories, 2438 Miyanoura, Kagoshima-shi, Kagoshima 891-1394, Japan