Influence of the estrus cycle on the evaluation of a vaginal irritation study in intact and ovariectomized rats-Reference-Cited by-同舟云学术

Influence of the estrus cycle on the evaluation of a vaginal irritation study in intact and ovariectomized rats

Published:2017 Issue:2 Volume:30 Page:161-168
ISSN:0914-9198
Container-title:Journal of Toxicologic Pathology
language:en
Short-container-title:J Toxicol Pathol

Author:

Ishii Aiko¹,Ogawa Bunichiro¹,Koyama Tomoko¹,Nakanishi Yutaka¹,Sasaki Minoru¹

Affiliation:

1. Drug Safety, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama-shi, Saitama 331-9530, Japan

Publisher

Japanese Society of Toxicologic Pathology

Subject

Toxicology,Pathology and Forensic Medicine

Link

https://www.jstage.jst.go.jp/article/tox/30/2/30_2016-0059/_pdf

Reference15 articles.

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2. 2. Eckstein P, Jackson MCN, Millman N, and Sobrero AJ. Comparison of vaginal tolerance tests of spermicidal preparations in rabbits and monkeys. J Reprod Fertil. 20: 85–93. 1969.

3. 3. Costin GE, Raabe HA, Priston R, Evans E, and Curren RD. Vaginal irritation models: the current status of available alternative and in vitro tests. Altern Lab Anim. 39: 317–337. 2011.

4. 4. Kaminsky M, and Willigan DA. pH and the potential irritancy of douche formulations to the vaginal mucosa of the albino rabbit and rat. Food Chem Toxicol. 20: 193–196. 1982.

5. 5. Kaminsky M, Szivos MM, Brown KR, and Willigan DA. Comparison of the sensitivity of the vaginal mucous membranes of the albino rabbit and laboratory rat to nonoxynol-9. Food Chem Toxicol. 23: 705–708. 1985.

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