Is there sufficient evidence to support the use of antibiotic holiday just before the second stage of an infected total hip or knee arthroplasty revision surgery?

Author:

Tsikopoulos Konstantinos,Sidiropoulos Konstantinos

Abstract

The practice of implementing an antibiotic holiday before the second stage of hip or knee arthroplasty is currently controversial due to limited evidence for this approach, as per the International Consensus Meeting 2018 on Musculoskeletal Infection. A greater understanding of this issue could augment the quality of Alrayes and Sukeik’s mini-review (2023) on diagnosing, managing, and treating periprosthetic knee infections. However, a significant lack of literature exists concerning the optimal duration for the antibiotic holiday, calling for more research before establishing any clinical guidelines.

Publisher

Baishideng Publishing Group Inc.

Reference17 articles.

1. Two-stage revision in periprosthetic knee joint infections

2. Fayaz H, Higuera CA, Shubnyakov I. International Consensus Meeting (ICM) 2018. What is the importance of two-week antibiotic holiday prior to reimplantation? Available from: https://icmphilly.com/questions/what-is-the-importance-of-two-week-antibiotic-holiday-prior-to-reimplantation/

3. Periprosthetic joint infection: current concepts and outlook

4. Determining the Role and Duration of the “Antibiotic Holiday” Period in Periprosthetic Joint Infection

5. Interval between two-stage exchanges: what is optimal and how do you know?

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