Author:
Chen Xiang-Xu,Tian Chu-Wei,Bai Li-Yong,Zhao Ya-Kuan,Zhang Cheng,Shi Liu,Zhang Yuan-Wei,Xie Wen-Jun,Zhu Huan-Yi,Chen Hui,Rui Yun-Feng
Abstract
The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance. To combat antimicrobial resistance, researchers have implemented various novel and innovative modalities to curb infections. Nanotechnology involves doping ions/metals onto the scaffolds to reach the target site to eradicate the infective foci. In this connotation, we reviewed silver nanoparticle technology in terms of mechanism of action, clinical applications, toxicity, and regulatory guidelines to treat orthopaedic infections.
Publisher
Baishideng Publishing Group Inc.
Subject
Orthopedics and Sports Medicine