Synthesis of 2,4,6-triarylpyridines Using AlPO4 Under Solvent-free Conditions

Abstract

A series of 2,4,6-triarylpyridines have been prepared using a variety of aromatic and heteroaromatic aldehydes in the presence of aluminum phosphate (AlPO4) as a heterogeneous catalyst at 120 oC under solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure, shorter reaction times, milder conditions and the catalyst exhibited remarkable reusable activity. Keywords: Aluminum phosphate; 2,4,6-triarylpyridines; One-pot synthesis; Shorter reaction times;  Reusable activity.  © 2010 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v2i2.3859               J. Sci. Res. 2 (2), 337-342 (2010)