Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model

Abstract

<p class="Abstract">The effectiveness of water decoction of <em>Tagetes patula</em> was studied against the chronic nonbacterial prostatitis in a rat model induced by estradiol  subcuta-neously in a castrated male rat. The low-dose decoction of <em>T. patula</em>  significantly ameliorated the prostatitis. The low-dose of polysaccharide and supernatant constituent of <em>T. patula</em> decreased the levels of IL-1?, TNF-?, PSA, and EGF, and improved the levels of testosterone and dihydrotestosterone in vivo. Further, the chemical study indicated that flavonoids were predominant in the supernatant constituent of <em>T. patula</em>. The flavonoids and polysaccha-rides were the effective constituents against prostatitis and this effect may be mediated by keeping hormone balance and a down-regulation of the in?ammatory mediator level of the prostate.</p><p><strong>Video Clip of Methodology</strong>:</p><p>9 min 43 Sec   <a href="https://www.youtube.com/v/udLMijALCZg">Full Screen</a>   <a href="https://www.youtube.com/watch?v=udLMijALCZg">Alternate</a></p>