Correlation between Histopathological Findings and Endoscopy in Esophageal Cance: Results in Khorramabad, Iran, Western Iran

Abstract

Background: Esophageal cancer is a cancer arising of the esophagus and during the past two decades, the epidemiology and treatment strategies for esophageal cancer have changed markedly in the Western Iran.The aim of this study is to investigate the clinical signs, endoscopy findings, and family history of esophageal cancer in the Khorramabad, Iran.Methods: In this cross-sectional research conducted during 1 year in 2015,96 patients had been diagnosed with esophageal cancer by endoscopy and pathological findings. The data collected through a multipart questionnaire includingage, sex, marital status, education, occupation, address and ethnicity, background as to smoking, alcohol consumption and history of gastric and esophageal cancers. The data were analyzed using chi-square test or Fisher exact test.Results: According to findings of this study, the most common clinical signs in the patients were Anorexia (53.1) and Weight Loss (62.5). The most common anatomical site of tumor in male was in the distal esophagus (41.3%) and middle esophagus in female patients (32%), which was statistically significant (P=0.047).Conclusions: In this study, distal esophageal cancer was more common. Abetter identification of Effective factors on esophageal cancer would result in better control and management of this disease.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.619-624