The Association of Allergy and Systemic Lupus Erythematosus as a Single Disease and an Overlapping Syndrome compared to Control Group

Abstract

Background:Allergic diseases and systemic lupus erythematosus (SLE) sometimes are being connected since both of these diseases are affected by gene-environment processes. SLE can appear coexisting with other autoimmune diseases as an overlapping syndrome. Objectives: This research was done to investigate the relation of allergic diseases and SLE as a single SLE or overlapping syndrome compared to control. Method: We collected data from 39 SLE only, 22 overlapping syndrome SLE, and 39 non SLE subjects who had filled an online Score for Allergic Rhinitis (SFAR) questionnaire. Results: There are significant outcomes of the existence of allergic disease (p=.007), atopic dermatitis (p=.000) and total number of allergies (p=.016) in SLE patients. There is a correlation of the appearance of allergy in SLE as a single or coexisting with other autoimmune disease compared to control group. Conclusion: Atopic dermatitis and the more number of allergic diseases that the one have, play role in appearing SLE. Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 916-919