MICROBIOLOGICAL ACTIVITY OF SILVER NANOPARTICLES STABILIZED WITH DEXTRAN DERIVATIVES

Abstract

The paper shows the microbiological activity of silver nanoparticles (AgNPs) stabilized with dextran derivatives with carbox-ymethyl dextran (CMD) and dextran sulfate (DS). Non-toxic, green procedures for the synthesis of AgNPs with CMD, DS were developed. The increasing application of silver nanoparticles in many areas, especially favors the so-called non-toxic, i.e. “green” synthesis procedures. Unlike physical and chemical synthetic methods, green synthesis has a number of advantages: lower energy consumption, simple execution, costs are reduced, use of non-toxic chemicals as reducing and stabilizing agents. Nanoparticles AgNPs-DS and AgNPs-CMD showed microbiological activity against the analyzed test microorgan-isms. Silver nanoparticles obtained in this way, due to their stability and preserved antimicrobial activity, can be widely used in various branches of industry. The results of testing the antimicrobial activity of synthesized nanoparticles from the technologi-cal aspects are important; these compounds have potential application in the biomedical field, and simple procedures have many advantages, such as low costs, compatibility for medical and pharmaceutical applications, as well as the production of other commercial products in the food industry.