Anesthetic Management of a Complex Regional Pain Syndrome (CRPS) Patient With Ketamine

Author:

Mundluru Tarun1,Saraghi Mana2

Affiliation:

1. Resident in Orofacial Pain and Oral Medicine, The Herman Ostrow School of Dentistry at the University of Southern California, Los Angeles, California,

2. Director, Dental Anesthesiology Residency Program, Jacobi Medical Center Bronx, New York

Abstract

Complex regional pain syndrome (CRPS) is a potentially debilitating form of neuropathic pain that may manifest following a traumatic injury or surgery. CRPS is also known as algodystrophy, causalgia, or reflex sympathetic dystrophy (RSD). Patients describe unbearable burning pain from nonnociceptive stimuli, such as when taking a shower or brushing against another object. Regular tactile stimuli encountered during routine dental procedures may not be well-tolerated by a patient with CRPS. Ketamine infusions have been reported to help alleviate acute exacerbations or “flare-ups” of CRPS symptoms. This case report provides a brief overview of CRPS pathophysiology and treatment including data supporting the use of ketamine infusions and a discussion regarding the anesthetic management of a patient with CRPS presenting for dental care under deep sedation utilizing high-dose intravenous ketamine.

Publisher

American Dental Society of Anesthesiology (ADSA)

Subject

Anesthesiology and Pain Medicine

Reference35 articles.

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2. Wasner G, Schattschneider J, Heckmann K, et al. Vascular abnormalities in reflex sympathetic dystrophy (CRPS I): mechanisms and diagnostic value. Brain. 2001; 124(pt 3): 587– 599.

3. Morgan GE, Mikhail MS, Murray MJ. Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill Companies;2013.

4. Ratti C, Nordio A, Resmini G, et al. Post-traumatic complex regional pain syndrome: clinical features and epidemiology. Clin Cases Miner Bone Metab. 2015; 12(suppl 1): 11– 16.

5. Guthmiller KB, Varacallo M. Complex Regional Pain Syndrome (CRPS), Reflex Sympathetic Dystrophy (RSD) [updated January 19, 2019]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK430719/. Accessed May 15, 2019.

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