Affiliation:
1. Professor and Chair and
2. Resident, Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania
Abstract
Abstract
The α-2 adrenergic receptor agonists have been used for decades to treat common medical conditions such as hypertension; attention-deficit/hyperactivity disorder; various pain and panic disorders; symptoms of opioid, benzodiazepine, and alcohol withdrawal; and cigarette craving.1 However, in more recent years, these drugs have been used as adjuncts for sedation and to reduce anesthetic requirements. This review will provide an historical perspective of this drug class, an understanding of pharmacological mechanisms, and an insight into current applications in clinical anesthesiology.
Publisher
American Dental Society of Anesthesiology (ADSA)
Subject
Anesthesiology and Pain Medicine
Reference41 articles.
1. The autonomic nervous system;Moss;Miller's Anesthesia. Vol 1. 6th ed,2005
2. A study of the adrenotropic receptors;Ahlquist;Am J Physiol,1948
3. The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ilium longitudinal muscle strip;Paton;Br J Pharmacol,1969
4. Selectivity of some alpha adrenoceptors in the normotensive rat;Van Meel;J Pharmacol Exp Ther,1981
5. Acute post-operative clonidine withdrawal syndrome;Brodsky;Anesthesiology,1976
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