ANALYSIS OF SOCIAL AND MEDICAL PORTRAIT OF CHILDREN WITH PERTUSSIS, MENINGOCOCCAL INFECTIOUS, SCARLET FEVER AND ESTIMATION OF THEIR ASSIGNED PHARMACOTHERAPY

Abstract

Introduction: The level of childhood bacterial diseases incidence does not have a downward trend. The aim: Conduction of a sociological analysis of medical cards for children with pertussis, meningococcal infection (MI), scarlet fever, and evaluation of consumed pharmacotherapy according to real clinical practice in Ukraine. Materials and methods: 1215 medical cards of inpatients; methods: sociological – document analysis, retrospective frequency. Results: Among the cards of children with pertussis: 50.2% – female, 49.8%– male; by age children up to 1 year (49.3%) were prevailed. In 79.6% incidence – medium-hard form pertussis, 42.2% with complications. Among patients with MI by sex there were: 50.5 % – boys and 49.5% – girls; by age – children aged 1-4 (40.2%); the structure of generalized forms of MI: 40.2% – meningococcemia, 11.4% – meningitis, 48.4% – combination. Scarlet fever was more frequently: boys (56.4%), children aged 5-9 (44.7%), urban residents (79.7%); it was 93.4% of a medium-hard form. Most of medicines were prescribed to children with MI – 15.8 trade names per 1 person, it was prescribed 191 INN, most often – Sodium chloride (90.0%), Ascorbic acid (68.5%), Ceftriaxone (65.8%); patients with pertussis – 11.2, 196 INN (Chlorpromazine (69.1%), Dexamethasone (53.2%), Butamirate (51.8%)); scarlet fever – 9.3 medicines, 114 INN (local action Comb drug for throat diseases treatment (94.4%), Ceftriaxone (48.7%), Metamizole sodium (38.1%)). Conclusions: Frequency analysis data of consumed pharmacotherapy in real pediatric practice in Ukraine shows the need for its further optimization in accordance with the principles of evidence-based medicine, the results of research on the socio-demographic characteristics of patients, forms and complications of course of the basic disease.