The Influence of the Application of Mineral Water on the Functional State of the Liver of Patients after Laparoscopic Cholecystektomia in the Long Period of Rehabilitation

Abstract

Aim: To determine the effectiveness of the influence of the use of mineral medicinal water on the functional state of the liver of patients after laparoscopic cholecystectomy in a long period of rehabilitation in the conditions of the Morshynkurort health resort complex. Materials and Methods: An analysis of 100 medical records of patients after laparoscopic cholecystectomy who were undergoing rehabilitation at the Morshynkurort health resort complex in 2017 and 2018 was carried out. Medical records were selected by a randomized method using the Random Allocation Rule program. Blinded evaluators while processing medical records. The method of comparison of indicators of the functional state of the liver of patients before the beginning of rehabilitation and after its completion was carried out by the method of mathematical statistics – Student’s t-test. The studied parameters: total protein (g/l), thymol test (unit), total bilirubin (mkmol/l), activity of alanine transpeptidase (ALT, (units/hour • l)), aspartate transaminase (AST, (units/hour • l)), total cholesterol (mmol/l), triglycerides (mmol/l), blood glucose (mmol/l). All patients were examined before and after treatment. There was no dropout from the study among the surveyed. Results: Mathematical statistics revealed a significant (p <0,05) improvement in such indicators as: thymol test, alanine transpeptidase activity, total cholesterol. Conclusions: Hydrotherapy for 14 days MPO well No. 3-k and groundwater source No. 4 in Morshyn diluted to mineralization 3,0-3,4 g/dm³ at a long stage of rehabilitation leads to an improvement in liver function in patients after laparoscopic cholecystectomy.