Affiliation:
1. SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE
2. BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE
Abstract
The aim: To assess morphometric parameters of placentas and to evaluate the correlation between the placental disk shape, the site of the umbilical cord insertion and the birth weight of dichorionic twins.
Materials and methods: The geometry of placentas, distances between umbilical cord insertion sites and the centroids of the disks were measured in 135 pairs of dichorionic diamniotic twins. The impact of the above-mentioned parameters on the birth weight and placental mass was analyzed.
Results: In terms of weight and geometric parameters of placentas, no proven discrepancy between different types of twins and inside pairs was found. A strong correlation was established between the placental weight and birth weight (r = 0.71, p < 0.05). Both the placental weight and birth weight showed the strong correlation with S*Circ (r = 0.62, p < 0.05). The displacement of the umbilical cord insertion site from the centroid of the placenta was negatively correlated with its mass (r = -0.428, p < 0.0001) and birth weight (r = -0.6115, p < 0.0001). The displacement along the maximum axis proved to play a significant role.
Conclusions: In dichorionic diamniotic twins, the area of the placentas plays the determining role in the functional activity of the organ, which increases when its shape approaches the circle. The area of the placenta multiplied by its circularity had the strongest correlation with birth weight and placental mass. The farther from the centre the umbilical cord is inserted, the lower the functional capacity of the placenta is.
Reference16 articles.
1. 1. Freedman A.A., Hogue C.J., Marsit C.J. et al. Associations Between Features of Placental Morphology and Birth Weight in Dichorionic Twins. Am J Epidemiol. 2019 ;188(3):518-526. doi: 10.1093/aje/kwy255.
2. 2. Grandi C., Veiga A., Mazzitelli N. et al. Medidas de crescimento placentário em relação ao peso de nascimento em uma população Latino-Americana. Rev Bras Ginecol e Obstet. 2016;38(8):373–80.
3. 3. Jelenkovic A., Sund R., Yokoyama Y. et al. Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts. Sci Rep. 2018;8(1):6300. doi: 10.1038/ s41598-018-24634-2.
4. 4. Osianlis T., Rombauts L., Gabbe M. et al. Incidence and zygosity of twin births following transfers using a single fresh or frozen embryo. Hum Reprod. 2014;29(7):1438-43. doi: 10.1093/humrep/deu064.
5. 5. Euro-Peristat Project. European Health Report. Core indicators of the health and care of pregnant women and babies in Europe in 2015. 2015.