Affiliation:
1. KHARKIV NATIONAL MEDICAL UNIVERSITY, KHARKIV, UKRAINE
Abstract
Aim: To develop clinical classification of liver cirrhosis, which can aid individualization and planning definitive treatment for this group of patients.
Materials and Methods: Computerized search of the literature was performed via PubMed using the following medical subject headings or keywords: “liver”, “cirrhosis” and “classification”; or “liver”, “cirrhosis” and “complications”; or “liver”, “cirrhosis” and “treatment”; or “portal” “, “hypertension” and “complications”. Articles were independently evaluated by each author, the etiological, morphological and current clinical classifications of LC were analyzed, their advantages and disadvantages identified, and after discussion classification of LC was developed by consensus.
Conclusions: The developed clinical classification of liver cirrhosis will facilitate the planning of therapeutic tactics for each patient, allow to personalize the treatment of patients with this pathology.
Reference25 articles.
1. 1. Roth GA, Abate D, Abate KH et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392(10159): 1736-1788. doi: 10.1016/S0140-6736(18)32203-7.
2. 2. Gu W, Hortlik H, Erasmus H-P et al. Trends and the course of liver cirrhosis and its complications in Germany: Nationwide populationbased study (2005 to 2018). The Lancet Regional Health – Europe. 2022;12: 100240. doi: 10.1016/j.lanepe.2021.100240.
3. 3. Gines P, Krag A, Abraldes JG et al. Liver cirrhosis Lancet. 2021;398(10308):1359-1376.doi: 10.1016/S0140-6736(21)01374-X.
4. 4. Shetty A, Jun Yum J, Saab S. The Gastroenterologist’s Guide to Preventive Management of Compensated Cirrhosis. Gastroenterol Hepatol (N Y). 2019;15(8):423-430.
5. 5. Heron M. Deaths: Leading Causes for 2016. Natl Vital Stat Rep. 2018;67(6):1-77.