EFFECT OF MAGNESIUM L!LACTATE SUPPLEMENT ON BLOOD PRESSURE AND CORRECTED QT INTERVAL IN A SAMPLE OF IRAQI WOMEN WITH METABOLIC SYNDROME-Reference-Cited by-同舟云学术

EFFECT OF MAGNESIUM L!LACTATE SUPPLEMENT ON BLOOD PRESSURE AND CORRECTED QT INTERVAL IN A SAMPLE OF IRAQI WOMEN WITH METABOLIC SYNDROME

Published:2023 Issue:2 Volume:76 Page:360-369
ISSN:0043-5147
Container-title:Wiadomości Lekarskie
language:en
Short-container-title:Wiad Lek

Author:

Hasan Ekhlas Khammas¹,Mshimesh Bahir Abdul Razzaq²,Rzoqi Shahbaa Shafeeq¹,Aziz Lewai Sharqi Abdul³,Khazaal Faris Abdul Kareem³,Marzooq Ahmed Abd³,Abudlqader Ehab Habeeb⁴

Affiliation:

1. AL-BAYAN UNIVERSITY, BAGHDAD, IRAQ

2. AL-MUSTANSIRIYAH UNIVERSITY, BAGHDAD, IRAQ

3. UNIVERSITY OF BAGHDAD, BAGHDAD, IRAQ

4. NAHRAIN UNIVERSITY, BAGHDAD, IRAQ

Abstract

The aim: The current study was designed for evaluation the effect of oral magnesium l-lactate supplementation on blood pressure and corrected QT interval in a sample of Iraqi women. Materials and methods: In this interventional prospective randomized trial, 58 female patients diagnosed with MetS according to the International Diabetic Federation (IDF) criteria and were randomly allocated to receive either placebo or magnesium l-lactate 84 mg, twice daily. Results: O#ce blood pressure showed a signi$cant drop in systolic blood pressure (SBP) (P<0.05), non-signi$cant decline in diastolic blood pressure (DBP), heart rate (HR), and pulse pressure (PP) (P>0.05), while ambulatory blood pressure monitoring (ABPM) recorded a signi$cant reduction in HR in patients on magnesium supplement. Also, there was a signi$cant decline in the SBP (P<0.05) and non-signi$cant decline in DBP and PP (P>0.05) in patients with masked hypertension on Mg supplement. The changes in corrected QT- interval had no signi$cant e"ect within Mg group (P>0.05). Conclusions: From above results, one can conclude that oral Mg l-lactate supplement can improve, to a certain extent, blood pressure of women with MetS. Further studies in this aspect may be required.

Publisher

ALUNA

Subject

General Medicine

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