ASSOCIATION OF CLINICAL AND EARLY ROUTINE LABORATORY FINDINGS WITH SEVERITY OF ACUTE PANCREATITIS

Abstract

The aim: To identify the association of clinical and simple laboratory data determined during hospitalization of the patient with severity of acute pancreatitis. Materials and methods: Clinical and laboratory parameters of 229 patients with acute pancreatitis were analyzed. All patients were divided into two groups depending on the severity of acute pancreatitis: in the group with mild AP were 130 (56.8%) patients and the group, which included moderately severe and severe degree of AP consisted of 99 (43.2%) patients. Results: The association of the age group of 61-70 years with the severity of acute pancreatitis was revealed (p 0.05). We did not find an association between the causes of acute pancreatitis and its severity. In the group with moderate-severe acute pancreatitis, the frequency of concomitant pathology was significantly higher than in the group with mild acute pancreatitis – 92.9% (92) and 78.5% (102) cases (p<0.05). The association between the severity of acute pancreatitis and the following laboratory parameters: blood sugar, leukocyte levels, the level of stabs, lymphocytes, total protein, serum amylase, urinary diastase, creatinine, ALT, AST, prothrombin index, neutrophil-lymphocyte ratio was revealed (p<0.05). Conclusions: The study did not reveal a significant difference between compared groups in the time of hospitalization; found no association between the causes of acute pancreatitis and its severity. Instead, the association between female sex, the presence of concomitant pathology and some routine laboratory findings with the severity of acute pancreatitis was proved.