CLINICAL CASE OF NEUROMYELITIS OPTICA SPECTRUM DISORDERS IN YOUNG WOMAN TREATED WITH RITUXIMAB

Author:

Poiasnyk Iryna M.1,Gryb Viktoriia A.1

Affiliation:

1. IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY, IVANO-FRANKIVSK, UKRAINE

Abstract

We report a case of a 28-year-old female who had the clinical manifestation of Neuromyelitis optica spectrum disorders with the area postrema syndrome at 24 years old. The patient presented with decreased vision due to acute optic neuritis, gait impairment, tetraplegia, sensory, and bladder disturbances. Magnetic resonance imaging of the spinal cord showed longitudinal high-intensity signals on a T2-weighted image in cervical and thoracic parts. Her serum and cerebrospinal fluid were positive for the anti-AQP4 antibody. The patient received high-dose methylprednisolone, plasmapheresis, but she remained free from relapses only after prescribing Rituximab. Prophylactic treatment of Neuromyelitis optica spectrum disorders recurrence must be immediately performed when it is identified because the progression of disability is related to the severity of attacks.

Publisher

ALUNA

Subject

General Medicine

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