CHANGES IN ARTICULAR CARTILAGE OF THE HIP JOINT INDUCED BY ACETABULAR LABRUM DAMAGE

Abstract

The aim: Histological studies of hip joint cartilage after articular labrum resection. Materials and methods: Articular labrum of hip joint was excised in adult rabbits. In 1,5 and 4 months, the histology of the joint was studied. The condi¬tion of the cartilage after reverse fixation of labrum was separately investigated. The morphology of the joint was assessed according to the OARSI scale and morphometric measurements. Results: The morphology of hip joint cartilage was changed after labrum resection including chondrocyte injury, cell heterogeneity and chondrocyte clus¬tering, less signs of fibrosis. Cartilage erosion was correlated with grade of OARSI scale, but not necessarily with cartilage thickness. The extracellular matrix / chondrocyte ratio was more significant indicator of cartilage condition than multipoint analysis of cartilage thickness. Conclusions: Injury of acetabular labrum cause change morphology of joint cartilage, which observed in the dynamics. In animal model the cartilage injury scoring scales are more accurate in long term studies while early changes can be interpreted with limitations.