THE LEVEL OF GROWTH STIMULATING FACTOR EXPRESSED BY GENE 2 AND TROPONIN I IN THE BLOOD PLASMA OF NSTEMI PATIENTS DEPENDING ON DIFFERENT CLINICAL CHARACTERISTICS

Abstract

The aim of the study is to evaluate the relationship between ST2 and Troponin I with various clinical and instrumental parameters. Materials and methods: We examined 200 patients with NSTEMI aged 38 to 80 years, who were urgently hospitalized in the Vinnytsya Regional Clinical Center of Cardiovascular Pathology. All patients underwent laboratory testing of ST2 and Troponin I levels in plasma by enzyme-linked immunosorbent assay on the first day of hospitalization before coronary angiography. Results: Elevations in ST2 levels were significantly higher in patients with acute heart failure (Killip III) and the presence of acute arrhythmias, diabetes mellitus, and smoking. The increase in Troponin I was associated primarily with the nature of changes in the ECG, stratification on the GRACE score and the presence of concomitant arterial hypertension. Conclusions: Determination of ST2 and Troponin I before coronary angiography makes it possible to predict the course of NSTEMI and make appropriate therapeutic corrections to prevent complications.